A response to claims of emergent intelligence and sentience in a dish
Fuat Balci, Suliann Ben Hamed, Thomas Boraud, Sébastien Bouret, Thomas Brochier, Cédric Brun, Jeremiah Y. Cohen, Etienne Coutureau, Marc Deffains, Valérie Doyère, Georgia G. Gregoriou, J. Alexander Heimel, Bjørg Elisabeth Kilavik, Daeyeol Lee, Eric C. Leuthardt, Zachary F. Mainen, Mackenzie Mathis, Ilya E. Monosov, Jérémie Naudé, Amy L. Orsborn, Camillo Padoa-Schioppa, Emmanuel Procyk, Bernardo Sabatini, Jérôme Sallet, Carmen Sandi, Jeffrey D. Schall, Alireza Soltani, Karel Svoboda, Charles R.E. Wilson, Jan Zimmermann
Neuron. 2023-03-01
10.1016/j.neuron.2023.02.009

Dichotomous activity and function of neurons with low- and high-frequency discharge in the external globus pallidus of non-human primates
Shiran Katabi, Avital Adler, Marc Deffains, Hagai Bergman
Cell Reports. 2023-01-01
10.1016/j.celrep.2022.111898

Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations
L. Iskhakova, P. Rappel, M. Deffains, G. Fonar, O. Marmor, R. Paz, Z. Israel, R. Eitan, H. Bergman
Nat Commun. 2021-12-02
10.1038/s41467-021-27375-5

Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia.
Joachim Mazere, Bixente Dilharreguy, Gwenaëlle Catheline, Marie Vidailhet, Marc Deffains, Delphine Vimont, Bastien Ribot, Elodie Barse, Laura Cif, Bernard Mazoyer, Nicolas Langbour, Antonio Pisani, Michèle Allard, Frédéric Lamare, Dominique Guehl, Philippe Fernandez, Pierre Burbaud
Brain. 2021-02-26
10.1093/brain/awaa465

The adaptive value of probability distortion and risk-seeking in macaques’ decision-making
A. Nioche, N. P. Rougier, M. Deffains, S. Bourgeois-Gironde, S. Ballesta, T. Boraud
Phil. Trans. R. Soc. B. 2021-01-11
10.1098/rstb.2019.0668

L‐DOPA regulates α‐synuclein accumulation in experimental parkinsonism
Marc Deffains, Marie‐Hélène Canron, Margaux Teil, Qin Li, Benjamin Dehay, Erwan Bezard, Pierre‐Olivier Fernagut
Neuropathol Appl Neurobiol. 2020-12-04
10.1111/nan.12678

What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?
Dan Valsky, Shai Heiman Grosberg, Zvi Israel, Thomas Boraud, Hagai Bergman, Marc Deffains
eLife. 2020-08-19
10.7554/elife.57445

Acute Striato-Cortical Synchronization Induces Focal Motor Seizures in Primates
Jerome Aupy, Bastien Ribot, Sandra Dovero, Nathalie Biendon, Tho-Hai Nguyen, Gregory Porras, Marc Deffains, Dominique Guehl, Pierre Burbaud
Cerebral Cortex. 2020-08-08
10.1093/cercor/bhaa212

Basal ganglia beta oscillations during sleep underlie Parkinsonian insomnia
Aviv D. Mizrahi-Kliger, Alexander Kaplan, Zvi Israel, Marc Deffains, Hagai Bergman
Proc. Natl. Acad. Sci. U.S.A.. 2020-07-07
10.1073/pnas.2001560117

In vivo electrophysiological validation of DREADD-based modulation of pallidal neurons in the non-human primate.
Marc Deffains, Tho Haï Nguyen, Hugues Orignac, Nathalie Biendon, Sandra Dovero, Erwan Bezard, Thomas Boraud
Eur J Neurosci. 2020-05-11
10.1111/ejn.14746

Parkinsonism-related β oscillations in the primate basal ganglia networks – Recent advances and clinical implications
Marc Deffains, Hagai Bergman
Parkinsonism & Related Disorders. 2019-02-01
10.1016/j.parkreldis.2018.12.015

Longer β oscillatory episodes reliably identify pathological subthalamic activity in Parkinsonism
Marc Deffains, Liliya Iskhakova, Shiran Katabi, Zvi Israel, Hagai Bergman
Mov Disord.. 2018-08-25
10.1002/mds.27418

Anesthesia reduces discharge rates in the human pallidum without changing the discharge rate ratio between pallidal segments
Anna Castrioto, Odeya Marmor, Marc Deffains, Dafna Willner, Eduard Linetsky, Hagai Bergman, Zvi Israel, Renana Eitan, David Arkadir
Eur J Neurosci. 2016-10-13
10.1111/ejn.13417

Stop! border ahead: Automatic detection of subthalamic exit during deep brain stimulation surgery
Dan Valsky, Odeya Marmor-Levin, Marc Deffains, Renana Eitan, Kim T. Blackwell, Hagai Bergman, Zvi Israel
Mov Disord.. 2016-10-06
10.1002/mds.26806

Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys
Marc Deffains, Liliya Iskhakova, Shiran Katabi, Suzanne N Haber, Zvi Israel, Hagai Bergman
eLife. 2016-08-23
10.7554/elife.16443

Stop and Think about Basal Ganglia Functional Organization: The Pallido-Striatal “Stop” Route
Marc Deffains, Liliya Iskhakova, Hagai Bergman
Neuron. 2016-01-01
10.1016/j.neuron.2016.01.003

Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease
Marc Deffains, Hagai Bergman
Mov Disord.. 2015-06-22
10.1002/mds.26300

Coinciding Decreases in Discharge Rate Suggest That Spontaneous Pauses in Firing of External Pallidum Neurons Are Network Driven
E. Schechtman, A. Adler, M. Deffains, H. Gabbay, S. Katabi, A. Mizrahi, H. Bergman
Journal of Neuroscience. 2015-04-29
10.1523/jneurosci.5232-14.2015

Higher neuronal discharge rate in the motor area of the subthalamic nucleus of Parkinsonian patients
Marc Deffains, Peter Holland, Shay Moshel, Fernando Ramirez de Noriega, Hagai Bergman, Zvi Israel
Journal of Neurophysiology. 2014-09-15
10.1152/jn.00170.2014

Importance of the temporal structure of movement sequences on the ability of monkeys to use serial order information
Marc Deffains, Eric Legallet, Paul Apicella
Exp Brain Res. 2011-08-20
10.1007/s00221-011-2839-0

The Role of Striatal Tonically Active Neurons in Reward Prediction Error Signaling during Instrumental Task Performance
P. Apicella, S. Ravel, M. Deffains, E. Legallet
Journal of Neuroscience. 2011-01-26
10.1523/jneurosci.4880-10.2011

Modulation of Neuronal Activity in the Monkey Putamen Associated With Changes in the Habitual Order of Sequential Movements
Marc Deffains, Eric Legallet, Paul Apicella
Journal of Neurophysiology. 2010-09-01
10.1152/jn.00355.2010

Tonically active neurons in the striatum differentiate between delivery and omission of expected reward in a probabilistic task context
Paul Apicella, Marc Deffains, Sabrina Ravel, Eric Legallet
European Journal of Neuroscience. 2009-08-01
10.1111/j.1460-9568.2009.06872.x