CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity
A. Fosch, D.S. Pizarro, S. Zagmutt, A.C. Reguera, G. Batallé, M. Rodríguez-García, J. García-Chica, O. Freire-Agulleiro, C. Miralpeix, P. Zizzari, D. Serra, L. Herrero, M. López, D. Cota, R. Rodríguez-Rodríguez, N. Casals
Molecular Metabolism. 2025-06-01
10.1016/j.molmet.2025.102155

GLP-1-mediated targeting of inflammation corrects obesogenic memory in male mice
Stéphane Léon, Julie Benoit, Samantha Clark, Philippe Zizzari, Bin Yang, Isabelle Dugail, Fatiha Merabtene, Karine Clement, Louise Eygret, Nathalie Dupuy, Jean-Christophe Delpech, Moïra Rossitto, Matthias Mack, Thierry Lesté-Lasserre, Brian Finan, Daniela Cota, Carmelo Quarta
Diabetes. 2025-04-11
10.2337/db24-1071

Engineered nasal bacteria: A new weapon against obesity?
Cristina Miralpeix, Daniela Cota
Cell Host & Microbe. 2025-04-01
10.1016/j.chom.2025.03.010

TGR5 receptors in SF1-expressing neurons of the ventromedial hypothalamus regulate glucose homeostasis
Philippe Zizzari, Ashley Castellanos-Jankiewicz, Selma Yagoub, Vincent Simon, Samantha Clark, Marlene Maître, Nathalie Dupuy, Thierry Leste-Lasserre, Delphine Gonzales, Kristina Schoonjans, Valérie S. Fénelon, Daniela Cota
Molecular Metabolism. 2025-01-01
10.1016/j.molmet.2024.102071

A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion
Mireia Montaner, Jessica Denom, Vincent Simon, Wanqing Jiang, Marie K. Holt, Daniel I. Brierley, Claude Rouch, Ewout Foppen, Nadim Kassis, David Jarriault, Dawood Khan, Louise Eygret, Francois Mifsud, David J. Hodson, Johannes Broichhagen, Lukas Van Oudenhove, Xavier Fioramonti, Victor Gault, Daniela Cota, Frank Reimann, Fiona M. Gribble, Stephanie Migrenne-Li, Stefan Trapp, Hirac Gurden, Christophe Magnan
Nat Commun. 2024-08-13
10.1038/s41467-024-51076-4

Single cell tracing of Pomc neurons reveals recruitment of ‘Ghost’ subtypes with atypical identity in a mouse model of obesity
Stéphane Leon, Vincent Simon, Thomas H. Lee, Lukas Steuernagel, Samantha Clark, Nasim Biglari, Thierry Lesté-Lasserre, Nathalie Dupuy, Astrid Cannich, Luigi Bellocchio, Philippe Zizzari, Camille Allard, Delphine Gonzales, Yves Le Feuvre, Emeline Lhuillier, Alexandre Brochard, Jean Charles Nicolas, Jérémie Teillon, Macha Nikolski, Giovanni Marsicano, Xavier Fioramonti, Jens C. Brüning, Daniela Cota, Carmelo Quarta
Nat Commun. 2024-04-24
10.1038/s41467-024-47877-2

A sympathetic brake on gut GLP-1 release
Antonio J. López-Gambero, Victor Jouque, Daniela Cota
Neuron. 2024-03-01
10.1016/j.neuron.2024.02.015

Antiobesity effects of intestinal gluconeogenesis are mediated by the brown adipose tissue sympathetic nervous system
Justine Vily‐Petit, Maud Soty‐Roca, Marine Silva, Manon Micoud, Félicie Evrard, Clara Bron, Margaux Raffin, Daniel Beiroa, Rubén Nogueiras, Damien Roussel, Amandine Gautier‐Stein, Fabienne Rajas, Daniela Cota, Gilles Mithieux
Obesity. 2024-02-04
10.1002/oby.23985

mTORC1 in energy expenditure: consequences for obesity
Camille Allard, Cristina Miralpeix, Antonio J. López-Gambero, Daniela Cota
Nat Rev Endocrinol. 2024-01-15
10.1038/s41574-023-00934-0

Poly-Agonist Pharmacotherapies for Metabolic Diseases: Hopes and New Challenges
Camille Allard, Daniela Cota, Carmelo Quarta
Drugs. 2023-12-21
10.1007/s40265-023-01982-6

Endocannabinoid-related molecules predict the metabolic efficacy of GLP-1 receptor agonism in humans with obesity
Isabelle Matias, E. W. Lehmann, Philippe Zizzari, S. Byberg, Daniela Cota, S. S. Torekov, Carmelo Quarta
J Endocrinol Invest. 2023-11-04
10.1007/s40618-023-02228-8

Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials.
Margaret Haney, Monique Vallée, Sandy Fabre, Stephanie Collins Reed, Marion Zanese, Ghislaine Campistron, Caroline A. Arout, Richard W. Foltin, Ziva D. Cooper, Tonisha Kearney-Ramos, Mathilde Metna, Zuzana Justinova, Charles Schindler, Etienne Hebert-Chatelain, Luigi Bellocchio, Adeline Cathala, Andrea Bari, Roman Serrat, David B. Finlay, Filippo Caraci, Bastien Redon, Elena Martín-García, Arnau Busquets-Garcia, Isabelle Matias, Frances R. Levin, François-Xavier Felpin, Nicolas Simon, Daniela Cota, Umberto Spampinato, Rafael Maldonado, Yavin Shaham, Michelle Glass, Lars Lykke Thomsen, Helle Mengel, Giovanni Marsicano, Stéphanie Monlezun, Jean-Michel Revest, Pier Vincenzo Piazza
Nat Med. 2023-06-01
10.1038/s41591-023-02381-w

The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice
Carlos Sepúlveda, Juan Manuel Rodríguez, Matías Monsalves-Álvarez, Camila Donoso-Barraza, Francisco Pino-de la Fuente, Isabelle Matías, Thierry Leste-Lasserre, Philippe Zizzari, Eugenia Morselli, Daniela Cota, Miguel Llanos, Rodrigo Troncoso
Biol Res. 2023-03-25
10.1186/s40659-023-00426-5

Chemogenetic stimulation of adult neurogenesis, and not neonatal neurogenesis, is sufficient to improve long-term memory accuracy
Marie Lods, Pierre Mortessagne, Emilie Pacary, Geoffrey Terral, Fanny Farrugia, Wilfrid Mazier, Nuria Masachs, Vanessa Charrier, Daniela Cota, Guillaume Ferreira, Djoher Nora Abrous, Sophie Tronel
Progress in Neurobiology. 2022-12-01
10.1016/j.pneurobio.2022.102364

Food intake and body weight in rodent studies: the devil is in the details
Camille Allard, Philippe Zizzari, Carmelo Quarta, Daniela Cota
Nat Metab. 2022-10-17
10.1038/s42255-022-00658-x

Insulin modulates emotional behavior through a serotonin-dependent mechanism
Hugo Martin, Sébastien Bullich, Maud Martinat, Mathilde Chataigner, Mathieu Di Miceli, Vincent Simon, Samantha Clark, Jasmine Butler, Mareike Schell, Simran Chopra, Francis Chaouloff, Andre Kleinridders, Daniela Cota, Philippe De Deurwaerdere, Luc Pénicaud, Sophie Layé, Bruno P. Guiard, Xavier Fioramonti
Mol Psychiatry. 2022-10-07
10.1038/S41380-022-01812-3

Expression of Functional Cannabinoid Type-1 (CB1) Receptor in Mitochondria of White Adipocytes
Antonio C. Pagano Zottola, Ilenia Severi, Astrid Cannich, Philippe Ciofi, Daniela Cota, Giovanni Marsicano, Antonio Giordano, Luigi Bellocchio
Cells. 2022-08-19
10.3390/cells11162582

Impaired quality of life, but not cognition, is linked to a history of chronic hypercortisolism in patients with Cushing’s disease in remission
Emilie Pupier, Alicia Santos, Nicole Etchamendy, Aurélie Lavielle, Amandine Ferriere, Aline Marighetto, Eugenia Resmini, Daniela Cota, Susan M. Webb, Antoine Tabarin
Front. Endocrinol.. 2022-08-08
10.3389/fendo.2022.934347

Paracrine actions of GLP1 in the gut unraveled
Camille Allard, Daniela Cota
Life Metabolism. 2022-07-01
10.1093/lifemeta/loac010

Yin-Yang control of energy balance by lipids in the hypothalamus: The endocannabinoids vs bile acids case
Thomas H. Lee, Daniela Cota, Carmelo Quarta
Biochimie. 2022-07-01
10.1016/j.biochi.2022.07.006

Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease
Antonio J. López-Gambero, Beatriz Pacheco-Sánchez, Cristina Rosell-Valle, Dina Medina-Vera, Juan Antonio Navarro, María del Mar Fernández-Arjona, Marialuisa de Ceglia, Carlos Sanjuan, Vincent Simon, Daniela Cota, Patricia Rivera, Fernando Rodríguez de Fonseca, Juan Suárez
Biomedicine & Pharmacotherapy. 2022-06-01
10.1016/j.biopha.2022.112994

Le récepteur hypothalamique TGR5 des acides biliaires
Valérie S. Fénelon, Daniela Cota
Med Sci (Paris). 2022-05-01
10.1051/medsci/2022052

Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model
Nadia Di Franco, Guillaume Drutel, Valérie Roullot-Lacarrière, Francisca Julio-Kalajzic, Valérie Lalanne, Agnès Grel, Thierry Leste-Lasserre, Isabelle Matias, Astrid Cannich, Delphine Gonzales, Vincent Simon, Daniela Cota, Giovanni Marsicano, Pier Vincenzo Piazza, Monique Vallée, Jean-Michel Revest
Molecular and Cellular Neuroscience. 2022-03-01
10.1016/j.mcn.2022.103705

The GhsrQ343X allele favors the storage of fat by acting on nutrient partitioning
Candice Marion, Philippe Zizzari, Raphael G P Denis, Rim Hassouna, Yacine Chebani, Thierry Leste-Lasserre, Hélène Doat, Gwenaëlle Le Pen, Daniela Cota, Florence Noble, Serge Luquet, Jacques Pantel
Journal of Endocrinology. 2021-12-01
10.1530/joe-20-0576

Microglial Cannabinoid Type 1 Receptor Regulates Brain Inflammation in a Sex-Specific Manner
Julia De Meij, Zain Alfanek, Lydie Morel, Fanny Decoeur, Quentin Leyrolle, Katherine Picard, Micael Carrier, Agnes Aubert, Alexandra Séré, Céline Lucas, Gerald Laforest, Jean-Christophe Helbling, Marie-Eve Tremblay, Daniela Cota, Marie-Pierre Moisan, Giovanni Marsicano, Sophie Layé, Agnès Nadjar
Cannabis and Cannabinoid Research. 2021-12-01
10.1089/can.2020.0170

Gut Microbiota and Mycobiota Evolution Is Linked to Memory Improvement after Bariatric Surgery in Obese Patients: A Pilot Study
Raphaël Enaud, Sophie Cambos, Esther Viaud, Erwan Guichoux, Emilie Chancerel, Aline Marighetto, Nicole Etchamendy, Samantha Clark, Kamel Mohammedi, Daniela Cota, Laurence Delhaes, Blandine Gatta-Cherifi
Nutrients. 2021-11-13
10.3390/nu13114061

Hypothalamic endocannabinoids in obesity: an old story with new challenges
Cristina Miralpeix, Ana Cristina Reguera, Anna Fosch, Sebastian Zagmutt, Núria Casals, Daniela Cota, Rosalía Rodríguez-Rodríguez
Cell. Mol. Life Sci.. 2021-10-31
10.1007/s00018-021-04002-6

Mass spectrometry imaging of mice brain lipid profile changes over time under high fat diet
Gianluca Sighinolfi, Samantha Clark, Landry Blanc, Daniela Cota, Boutayna Rhourri-Frih
Sci Rep. 2021-10-04
10.1038/s41598-021-97201-x

Functional heterogeneity of POMC neurons relies on mTORC1 signaling
Nicolas Saucisse, Wilfrid Mazier, Vincent Simon, Elke Binder, Caterina Catania, Luigi Bellocchio, Roman A. Romanov, Stéphane Léon, Isabelle Matias, Philippe Zizzari, Carmelo Quarta, Astrid Cannich, Kana Meece, Delphine Gonzales, Samantha Clark, Julia M. Becker, Giles S.H. Yeo, Xavier Fioramonti, Florian T. Merkle, Sharon L. Wardlaw, Tibor Harkany, Federico Massa, Giovanni Marsicano, Daniela Cota
Cell Reports. 2021-10-01
10.1016/j.celrep.2021.109800

The temporal origin of dentate granule neurons dictates their role in spatial memory
Nuria Masachs, Vanessa Charrier, Fanny Farrugia, Valerie Lemaire, Nicolas Blin, Wilfrid Mazier, Sophie Tronel, Marie-Françoise Montaron, Shaoyu Ge, Giovanni Marsicano, Daniela Cota, Véronique Deroche-Gamonet, Cyril Herry, Djoher Nora Abrous
Mol Psychiatry. 2021-09-15
10.1038/s41380-021-01276-x

Central anorexigenic actions of bile acids are mediated by TGR5
Alessia Perino, Laura. A. Velázquez-Villegas, Nadia Bresciani, Yu Sun, Qingyao Huang, Valérie S. Fénelon, Ashley Castellanos-Jankiewicz, Philippe Zizzari, Giuseppe Bruschetta, Sungho Jin, Aiste Baleisyte, Antimo Gioiello, Roberto Pellicciari, Julijana Ivanisevic, Bernard L. Schneider, Sabrina Diano, Daniela Cota, Kristina Schoonjans
Nat Metab. 2021-05-01
10.1038/s42255-021-00398-4

Adult-born neurons immature during learning are necessary for remote memory reconsolidation in rats
Marie Lods, Emilie Pacary, Wilfrid Mazier, Fanny Farrugia, Pierre Mortessagne, Nuria Masachs, Vanessa Charrier, Federico Massa, Daniela Cota, Guillaume Ferreira, Djoher Nora Abrous, Sophie Tronel
Nat Commun. 2021-03-19
10.1038/s41467-021-22069-4

Inhibition of mTOR signaling by genetic removal of p70 S6 kinase 1 increases anxiety-like behavior in mice
Muriel Koehl, Elodie Ladevèze, Caterina Catania, Daniela Cota, Djoher Nora Abrous
Transl Psychiatry. 2021-03-15
10.1038/s41398-020-01187-5

POMC neuronal heterogeneity in energy balance and beyond: an integrated view
Carmelo Quarta, Marc Claret, Lori M. Zeltser, Kevin W. Williams, Giles S. H. Yeo, Matthias H. Tschöp, Sabrina Diano, Jens C. Brüning, Daniela Cota
Nat Metab. 2021-02-25
10.1038/s42255-021-00345-3

A Novel Cortical Mechanism for Top-Down Control of Water Intake.
Zhe Zhao, Edgar Soria-Gómez, Marjorie Varilh, Ana Covelo, Francisca Julio-Kalajzić, Astrid Cannich, Adriana Castiglione, Léonie Vanhoutte, Alexia Duveau, Philippe Zizzari, Anna Beyeler, Daniela Cota, Luigi Bellocchio, Arnau Busquets-Garcia, Giovanni Marsicano
Current Biology. 2020-12-01
10.1016/j.cub.2020.09.011

CB1 and GLP-1 Receptors Cross-Talk Provides New Therapies for Obesity
Philippe Zizzari, Rongjun He , Sarah Falk, Luigi Bellocchio, Camille Allard, Samantha Clark, Thierry Lesté-Lasserre, Giovanni Marsicano, Christoffer Clemmensen, Diego Perez-Tilve , Brian Finan, Daniela Cota, Carmelo Quarta.
Diabetes. 2020-10
10.2337/db20-0162

In silico Hierarchical Clustering of Neuronal Populations in the Rat Ventral Tegmental Area Based on Extracellular Electrophysiological Properties
Mathieu Di Miceli, Zoé Husson, Philippe Ruel, Sophie Layé, Daniela Cota, Xavier Fioramonti, Clémentine Bosch-Bouju, Benjamin Gronier
Front. Neural Circuits. 2020-08-13
10.3389/fncir.2020.00051

Calcitonin gene-related peptide-induced phosphorylation of STAT3 in arcuate neurons is a link in the metabolic benefits of portal glucose.
Maud Soty, Justine Vily-Petit, Ashley Castellanos-Jankiewicz, Omar Guzman-Quevedo, Margaux Raffin, Samantha Clark, Marine Silva, Amandine Gautier-Stein, Daniela Cota, Gilles Mithieux
Neuroendocrinology. 2020-06-09
10.1159/000509230

Effects of a High-Protein Diet on Cardiometabolic Health, Vascular Function, and Endocannabinoids-A PREVIEW Study.
Lea Tischmann, Mathijs Drummen, Peter Joris, Blandine Gatta-Cherifi, Anne Raben, Mikael Fogelholm, Isabelle Matias, Daniela Cota, Ronald Mensink, Margriet Westerterp-Plantenga, Tanja Adam
Nutrients. 2020-05-22
10.3390/nu12051512

Role of Endocannabinoids in Energy-Balance Regulation in Participants in the Postobese State-a PREVIEW Study.
Mathijs Drummen, Lea Tischmann, Blandine Gatta-Cherifi, Daniela Cota, Isabelle Matias, Anne Raben, Tanja Adam, Margriet Westerterp-Plantenga
The Journal of Clinical Endocrinology & Metabolism. 2020-04-25
10.1210/clinem/dgaa193

Anti-obesity therapy with peripheral CB1 blockers: from promise to safe(?) practice
Carmelo Quarta, Daniela Cota
Int J Obes. 2020-04-21
10.1038/s41366-020-0577-8

Inhibition of mTOR signaling by genetic removal of p70 S6 Kinase 1 leads to anxiety-like disorders
Muriel Koehl, Elodie Ladeveze, Caterina Catania, Daniela Cota, Djoher Nora Abrous
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10.1101/2020.03.25.007427

POMC Neurons Dysfunction in Diet-induced Metabolic Disease: Hallmark or Mechanism of Disease?
Carmelo Quarta, Xavier Fioramonti, Daniela Cota
Neuroscience. 2019-11-01
10.1016/j.neuroscience.2019.09.031

mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability
Wilfrid Mazier, Nicolas Saucisse, Vincent Simon, Astrid Cannich, Giovanni Marsicano, Federico Massa, Daniela Cota
Molecular Metabolism. 2019-10-01
10.1016/j.molmet.2019.08.005

Effects of a High-Protein/Moderate-Carbohydrate Diet on Appetite, Gut Peptides, and Endocannabinoids-A Preview Study
Lea Tischmann, Mathijs Drummen, Blandine Gatta-Cherifi, Anne Raben, Mikael Fogelholm, Bolette Hartmann, Jens J. Holst, Isabelle Matias, Daniela Cota, Ronald P. Mensink, Peter J. Joris, Margriet S. Westerterp-Plantenga, Tanja C. Adam
Nutrients. 2019-09-21
10.3390/nu11102269

Top-down control of water intake by the endocannabinoid system
Zhe Zhao, Edgar Soria-Gómez, Marjorie Varilh, Francisca Julio-Kalajzić, Astrid Cannich, Adriana Castiglione, Léonie Vanhoutte, Alexia Duveau, Philippe Zizzari, Anna Beyeler, Daniela Cota, Luigi Bellocchio, Arnau Busquets-Garcia, Giovanni Marsicano
Preprint bioRxiv. 2019-08-09
10.1101/729970

The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system
Khalil Bouyakdan, Hugo Martin, Fabienne Liénard, Lionel Budry, Bouchra Taib, Demetra Rodaros, Chloé Chrétien, Éric Biron, Zoé Husson, Daniela Cota, Luc Pénicaud, Stephanie Fulton, Xavier Fioramonti, and Thierry Alquier
J Clin Invest. 2019-04-02
10.1172/JCI123454

Sequential alteration of microglia and astrocytes in the rat thalamus following spinal nerve ligation.
Lucie Blaszczyk, Marlène Maître, Thierry Lesté-Lasserre, Samantha Clark, Daniela Cota, Stéphane H. R. Oliet, Valérie S. Fénelon
J Neuroinflammation. 2018-12-15
10.1186/s12974-018-1378-z

Oea Signaling Pathways and the Metabolic Benefits of Vertical Sleeve Gastrectomy.
Chelsea R. Hutch, Danielle R. Trakimas, Karen Roelofs, Joshua Pressler, Joyce Sorrell, Daniela Cota, Silvana Obici, Darleen A. Sandoval
Annals of Surgery. 2018-11-01
10.1097/sla.0000000000003093

Étude des interactions entre le système endocannabinoïde et la pathologie de l’axe corticotrope chez l’Homme
F. Verdier, A. Ferrière, M. Haïssaguerre, J. Teynié, P. Perez, R. Sitta, D. Cota, I. Matias, B. Gatta-Cherifi, A. Tabarin
Annales d'Endocrinologie. 2018-09-01
10.1016/j.ando.2018.06.271

mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin.
Magalie Haissaguerre, Amandine Ferrière, Vincent Simon, Nicolas Saucisse, Nathalie Dupuy, Caroline André, Samantha Clark, Omar Guzman-Quevedo, Antoine Tabarin, Daniela Cota
Molecular Metabolism. 2018-06-01
10.1016/j.molmet.2018.04.002

NPV-BSK805, an Antineoplastic Jak2 Inhibitor Effective in Myeloproliferative Disorders, Causes Adiposity in Mice by Interfering With the Action of Leptin.
Magalie Haissaguerre, Amandine Ferriere, Samantha Clark, Omar Guzman-Quevedo, Antoine Tabarin, Daniela Cota
Front. Pharmacol.. 2018-05-15
10.3389/fphar.2018.00527

mTORC1 pathway disruption abrogates the effects of the ciliary neurotrophic factor on energy balance and hypothalamic neuroinflammation.
Caroline André, Caterina Catania, Julie Remus-Borel, Elodie Ladeveze, Thierry Leste-Lasserre, Wilfrid Mazier, Elke Binder, Delphine Gonzales, Samantha Clark, Omar Guzman-Quevedo, Djoher Nora Abrous, Sophie Layé, Daniela Cota
Brain, Behavior, and Immunity. 2018-05-01
10.1016/j.bbi.2018.03.014

Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling.
Joaquim Javary, Nathalie Allain-Courtois, Nicolas Saucisse, Pierre Costet, Capucine Heraud, Fadila Benhamed, Rémi Pierre, Corinne Bure, Nestor Pallares-Lupon, Marcio Do Cruzeiro, Catherine Postic, Daniela Cota, Pierre Dubus, Jean Rosenbaum, Samira Benhamouche-Trouillet
Gut. 2017-10-26
10.1136/gutjnl-2017-314208

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.
Inigo Ruiz de Azua, Giacomo Mancini, Raj Kamal Srivastava, Alejandro Aparisi Rey, Pierre Cardinal, Laura Tedesco, Cristina Maria Zingaretti, Antonia Sassmann, Carmelo Quarta, Claudia Schwitter, Andrea Conrad, Nina Wettschureck, V. Kiran Vemuri, Alexandros Makriyannis, Jens Hartwig, Maria Mendez-Lago, Laura Bindila, Krisztina Monory, Antonio Giordano, Saverio Cinti, Giovanni Marsicano, Stefan Offermanns, Enzo Nisoli, Uberto Pagotto, Daniela Cota, Beat Lutz
Journal of Clinical Investigation. 2017-10-16
10.1172/jci83626

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Carmelo Quarta, Christoffer Clemmensen, Zhimeng Zhu, Bin Yang, Sini S. Joseph, Dominik Lutter, Chun-Xia Yi, Elisabeth Graf, Cristina García-Cáceres, Beata Legutko, Katrin Fischer, Robert Brommage, Philippe Zizzari, Bernardo S. Franklin, Martin Krueger, Marco Koch, Sabine Vettorazzi, Pengyun Li, Susanna M. Hofmann, Mostafa Bakhti, Aimée Bastidas-Ponce, Heiko Lickert, Tim M. Strom, Valerie Gailus-Durner, Ingo Bechmann, Diego Perez-Tilve, Jan Tuckermann, Martin Hrabě de Angelis, Darleen Sandoval, Daniela Cota, Eicke Latz, Randy J. Seeley, Timo D. Müller, Richard D. DiMarchi, Brian Finan, Matthias H. Tschöp
Cell Metabolism. 2017-10-01
10.1016/j.cmet.2017.08.023

The brain strikes back: Hypothalamic targets for peripheral CB1 receptor inverse agonism.
Daniela Cota
Molecular Metabolism. 2017-10-01
10.1016/j.molmet.2017.07.003

Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits.
Benjamin K. Lau, Daniela Cota, Luigia Cristino, Stephanie L. Borgland
Neuropharmacology. 2017-09-01
10.1016/j.neuropharm.2017.05.033

MECHANISMS IN ENDOCRINOLOGY: Endocannabinoids and metabolism: past, present and future.
Vincent Simon, Daniela Cota
European Journal of Endocrinology. 2017-06-01
10.1530/eje-16-1044

Nutritional status-dependent endocannabinoid signalling regulates the integration of rat visceral information.
Abdessattar Khlaifia, Isabelle Matias, Daniela Cota, Fabien Tell
J Physiol. 2017-03-27
10.1113/jp273484

The CB1 Receptor as the Cornerstone of Exostasis.
Pier Vincenzo Piazza, Daniela Cota, Giovanni Marsicano
Neuron. 2017-03-01
10.1016/j.neuron.2017.02.002

Islet Endothelial Cell: Friend and Foe.
Wilfrid Mazier, Daniela Cota
Endocrinology. 2017-02-01
10.1210/en.2016-1925

The Fat Side of the Endocannabinoid System: Role of Endocannabinoids in the Adipocyte
Isabelle Matias, Ilaria Belluomo, Daniela Cota
Cannabis and Cannabinoid Research. 2016-12-01
10.1089/can.2016.0014

Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation.
Caroline André, Omar Guzman-Quevedo, Charlotte Rey, Julie Rémus-Borel, Samantha Clark, Ashley Castellanos-Jankiewicz, Elodie Ladeveze, Thierry Leste-Lasserre, Agnes Nadjar, Djoher Nora Abrous, Sophie Laye, Daniela Cota
Diabetes. 2016-11-30
10.2337/db16-0586

The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease.
Mazier W, Saucisse N, Gatta-Cherifi B, Cota D.
Trends Endocrinol Metab..
https://doi.org/10.1016/j.tem.2015.07.007

The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease.
Wilfrid Mazier, Nicolas Saucisse, Blandine Gatta-Cherifi, Daniela Cota
Trends in Endocrinology & Metabolism. 2015-10-01
10.1016/j.tem.2015.07.007

New insights on the role of the endocannabinoid system in the regulation of energy balance.
B Gatta-Cherifi, D Cota
Int J Obes. 2015-09-16
10.1038/ijo.2015.179

Endocannabinoids and Metabolic Disorders.
Blandine Gatta-Cherifi, Daniela Cota
Handbook of Experimental Pharmacology. 2015-01-01
10.1007/978-3-319-20825-1_13

[Role of the mTOR pathway in the central regulation of energy balance].
Magalie Haissaguerre, Daniela Cota
Biologie Aujourd'hui. 2015-01-01
10.1051/jbio/2016009

Influence of mTOR in energy and metabolic homeostasis.
Magalie Haissaguerre, Nicolas Saucisse, Daniela Cota
Molecular and Cellular Endocrinology. 2014-11-01
10.1016/j.mce.2014.07.015

CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin.
Pierre Cardinal, Caroline André, Carmelo Quarta, Luigi Bellocchio, Samantha Clark, Melissa Elie, Thierry Leste-Lasserre, Marlene Maitre, Delphine Gonzales, Astrid Cannich, Uberto Pagotto, Giovanni Marsicano, Daniela Cota
Molecular Metabolism. 2014-10-01
10.1016/j.molmet.2014.07.004

mTORC2, the "other" mTOR, is a new player in energy balance regulation.
Daniela Cota
Molecular Metabolism. 2014-07-01
10.1016/j.molmet.2014.04.002

Leucine supplementation protects from insulin resistance by regulating adiposity levels.
Elke Binder, Francisco J. Bermúdez-Silva, Caroline André, Melissa Elie, Silvana Y. Romero-Zerbo, Thierry Leste-Lasserre, llaria Belluomo, Adeline Duchampt, Samantha Clark, Agnes Aubert, Marco Mezzullo, Flaminia Fanelli, Uberto Pagotto, Sophie Layé, Gilles Mithieux, Daniela Cota
PLoS ONE. 2013-09-25
10.1371/journal.pone.0074705

Leucine supplementation modulates fuel substrates utilization and glucose metabolism in previously obese mice.
Elke Binder, Francisco Javier Bermúdez-Silva, Melissa Elie, Thierry Leste-Lasserre, Ilaria Belluomo, Samantha Clark, Adeline Duchampt, Gilles Mithieux, Daniela Cota
Obesity. 2013-09-05
10.1002/oby.20578

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB₁ receptor blockade.
L. Bellocchio, E. Soria-Gomez, C. Quarta, M. Metna-Laurent, P. Cardinal, E. Binder, A. Cannich, A. Delamarre, M. Haring, M. Martin-Fontecha, D. Vega, T. Leste-Lasserre, D. Bartsch, K. Monory, B. Lutz, F. Chaouloff, U. Pagotto, M. Guzman, D. Cota, G. Marsicano
Proceedings of the National Academy of Sciences. 2013-03-04
10.1073/pnas.1218573110

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB1 receptor blockade
Luigi Bellocchio, Edgar Soria-Gómez, Carmelo Quarta, Mathilde Metna-Laurent, Pierre Cardinal, Elke Binder, Astrid Cannich, Anna Delamarre, Martin Häring, Mar Martín-Fontecha, David Vega, Thierry Leste-Lasserre, Dusan Bartsch, Krisztina Monory, Beat Lutz, Francis Chaouloff, Uberto Pagotto, Manuel Guzman, Daniela Cota, Giovanni Marsicano
Proc. Natl. Acad. Sci. U.S.A.. 2013-03-04
10.1073/pnas.1218573110

P2101 Effet d’un régime hypoglucidique sur le métabolisme et les concentrations plasmatiques des endocannabinoïdes chez des patients diabétiques de type 2
B. Gatta Cherifi, E. Maury, I. Belluomo, M. Isabelle, I. Matias, A. Tabarin, D. Cota, V. Rigalleau
Diabetes & Metabolism. 2013-03-01
10.1016/s1262-3636(13)72011-1

Un nouveau biomarqueur de l’obésité humaine : les endocannabinoïdes salivaires
B. Gatta-Cherifi, I. Matias, A. Tabarin, S. Clark, T. Lestte-Lasserre, G. Marsicano, P.V. Piazza, D. Cota
Annales d'Endocrinologie. 2012-09-01
10.1016/j.ando.2012.07.733

Obesity and the Endocannabinoid System: Circulating Endocannabinoids and Obesity
Isabelle Matias, Blandine Gatta-Cherifi, Daniela Cota
Curr Obes Rep. 2012-08-17
10.1007/s13679-012-0027-6

Coupling nutrient sensing to metabolic homoeostasis: the role of the mammalian target of rapamycin complex 1 pathway.
Caroline André, Daniela Cota
Proc. Nutr. Soc.. 2012-08-09
10.1017/s0029665112000754

Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice.
M. Bajzer, M. Olivieri, M. K. Haas, P. T. Pfluger, I. J. Magrisso, M. T. Foster, M. H. Tschöp, K. A. Krawczewski-Carhuatanta, D. Cota, S. Obici
Diabetologia. 2011-10-11
10.1007/s00125-011-2302-6

Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity.
B Gatta-Cherifi, I Matias, M Vallée, A Tabarin, G Marsicano, P V Piazza, D Cota
Int J Obes Relat Metab Disord. 2011-08-16
10.1038/ijo.2011.165

The role of the endocannabinoid system in the neuroendocrine regulation of energy balance.
Francisco Javier Bermudez-Silva, Pierre Cardinal, Daniela Cota
J Psychopharmacol. 2011-08-08
10.1177/0269881111408458

Synergistic post-prandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity
B. Gatta-Cherifi, I. Matias, M. Vallee, A. Tabarin, G. Marsicano, P.V. Piazza, D. Cota
Appetite. 2011-07-01
10.1016/j.appet.2011.05.174

mTORC1 signaling in energy balance and metabolic disease.
C Catania, E Binder, D Cota
Int J Obes. 2010-09-28
10.1038/ijo.2010.208

Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status.
Eneida C. Villanueva, Heike Münzberg, Daniela Cota, Rebecca L. Leshan, Keely Kopp, Ryoko Ishida-Takahashi, Justin C. Jones, Diane C. Fingar, Randy J. Seeley, Martin G. Myers
Endocrinology. 2009-10-01
10.1210/en.2009-0642

Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and obesity.
Daniela Cota
Physiology & Behavior. 2009-07-01
10.1016/j.physbeh.2009.03.006

Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism.
Daniela Cota, Darleen A. Sandoval, Massimiliano Olivieri, Elena Prodi, David A. D'Alessio, Stephen C. Woods, Randy J. Seeley, Silvana Obici
Obesity. 2009-03-26
10.1038/oby.2009.84

Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system.
K. Proulx, D. Cota, S. C. Woods, R. J. Seeley
Diabetes. 2008-09-05
10.2337/db07-1690

Regulation of food intake through hypothalamic signaling networks involving mTOR.
Stephen C Woods, Randy J Seeley, Daniela Cota
Annu. Rev. Nutr.. 2008-08-01
10.1146/annurev.nutr.28.061807.155505

The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity.
D. Cota, E. K. Matter, S. C. Woods, R. J. Seeley
Journal of Neuroscience. 2008-07-09
10.1523/JNEUROSCI.1389-08.2008

The role of the endocannabinoid system in the regulation of hypothalamic-pituitary-adrenal axis activity.
D. Cota
J Neuroendocrinol. 2008-05-01
10.1111/j.1365-2826.2008.01673.x

Role of the endocannabinoid system in energy balance regulation and obesity.

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10.1159/0000115362

The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation.
Darleen Sandoval, Daniela Cota, Randy J. Seeley
Annu. Rev. Physiol.. 2008-03-01
10.1146/annurev.physiol.70.120806.095256

The role of CNS fuel sensing in energy and glucose regulation.
Daniela Cota, Karine Proulx, Randy J. Seeley
Gastroenterology. 2007-05-01
10.1053/j.gastro.2007.03.049

CB1 receptors: emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health.
Daniela Cota
Diabetes Metab. Res. Rev.. 2007-01-01
10.1002/dmrr.764

Leptin in energy balance and reward: two faces of the same coin?
Daniela Cota, Jason G. Barrera, Randy J. Seeley
Neuron. 2006-09-01
10.1016/j.neuron.2006.09.009

Cannabinoids, opioids and eating behavior: the molecular face of hedonism?
Daniela Cota, Matthias H. Tschöp, Tamas L. Horvath, Allen S. Levine
Brain Research Reviews. 2006-06-01
10.1016/j.brainresrev.2005.10.004

Hypothalamic mTOR signaling regulates food intake.
D. Cota
Science. 2006-05-12
10.1126/science.1124147

Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity.
Karine Proulx, Daniela Cota, Tamara R. Castañeda, Matthias H. Tschöp, David A. D'Alessio, Patrick Tso, Stephen C. Woods, Randy J. Seeley
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2005-09-01
10.1152/ajpregu.00029.2005

Antagonizing the cannabinoid receptor type 1: a dual way to fight obesity.
D. Cota, S. Genghini, R. Pasquali, U. Pagotto
J Endocrinol Invest. 2003-10-01
10.1007/bf03348205

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis.
Daniela Cota, Giovanni Marsicano, Matthias Tschöp, Yvonne Grübler, Cornelia Flachskamm, Mirjam Schubert, Dorothee Auer, Alexander Yassouridis, Christa Thöne-Reineke, Sylvia Ortmann, Federica Tomassoni, Cristina Cervino, Enzo Nisoli, Astrid C.E. Linthorst, Renato Pasquali, Beat Lutz, Günter K. Stalla, Uberto Pagotto
J. Clin. Invest.. 2003-08-01
10.1172/JCI200317725

Cannabinoids in energy balance and prospectives in the therapy of obesity
G. Marsicano, D. Cota, G. Stalla, R. Pasquali, U. Pagotto, B. Lutz
CMCCNSA. 2003-06-01
10.2174/1568015033477839

Relationship between socio-economic and cultural status, psychological factors and body fat distribution in middle-aged women living in Northern Italy.
D. Cota, V. Vicennati, L. Ceroni, A. M. Morselli-Labate, Renato Pasquali
Eat Weight Disord. 2001-12-01
10.1007/bf03339744