Our team studies how the immune system and the central nervous system communicate, both under healthy conditions and during disease. We are particularly interested in how this two-way “neuroimmune” dialogue shapes whole-body metabolism, in both males and females.

A major focus of our research is the interaction between microglia—the brain’s resident immune cells—and neurons. We explore how these interactions are influenced by diet, with a special emphasis on the role of lipids in regulating microglial physiology. Beyond microglia, we also investigate how other types of immune cells contribute to systemic metabolic regulation.

To address these questions, we combine a broad range of approaches, from cell and molecular physiology to in vivo models and behavioral studies.

Ultimately, by uncovering the mechanisms of neuroimmune communication, we aim to understand how lifestyle and diet influence whole-body metabolism, and to open new avenues for preventing or treating metabolic and neurological diseases.