TGR5 receptors in SF1-expressing neurons of the ventromedial hypothalamus regulate glucose homeostasis
Philippe Zizzari, Ashley Castellanos-Jankiewicz, Selma Yagoub, Vincent Simon, Samantha Clark, Marlene Maître, Nathalie Dupuy, Thierry Leste-Lasserre, Delphine Gonzales, Kristina Schoonjans, Valérie S. Fénelon, Daniela Cota
Molecular Metabolism. 2025-01-01
10.1016/j.molmet.2024.102071

A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion
Mireia Montaner, Jessica Denom, Vincent Simon, Wanqing Jiang, Marie K. Holt, Daniel I. Brierley, Claude Rouch, Ewout Foppen, Nadim Kassis, David Jarriault, Dawood Khan, Louise Eygret, Francois Mifsud, David J. Hodson, Johannes Broichhagen, Lukas Van Oudenhove, Xavier Fioramonti, Victor Gault, Daniela Cota, Frank Reimann, Fiona M. Gribble, Stephanie Migrenne-Li, Stefan Trapp, Hirac Gurden, Christophe Magnan
Nat Commun. 2024-08-13
10.1038/s41467-024-51076-4

Single cell tracing of Pomc neurons reveals recruitment of ‘Ghost’ subtypes with atypical identity in a mouse model of obesity
Stéphane Leon, Vincent Simon, Thomas H. Lee, Lukas Steuernagel, Samantha Clark, Nasim Biglari, Thierry Lesté-Lasserre, Nathalie Dupuy, Astrid Cannich, Luigi Bellocchio, Philippe Zizzari, Camille Allard, Delphine Gonzales, Yves Le Feuvre, Emeline Lhuillier, Alexandre Brochard, Jean Charles Nicolas, Jérémie Teillon, Macha Nikolski, Giovanni Marsicano, Xavier Fioramonti, Jens C. Brüning, Daniela Cota, Carmelo Quarta
Nat Commun. 2024-04-24
10.1038/s41467-024-47877-2

Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease
Antonio J. López-Gambero, Beatriz Pacheco-Sánchez, Cristina Rosell-Valle, Dina Medina-Vera, Juan Antonio Navarro, María del Mar Fernández-Arjona, Marialuisa de Ceglia, Carlos Sanjuan, Vincent Simon, Daniela Cota, Patricia Rivera, Fernando Rodríguez de Fonseca, Juan Suárez
Biomedicine & Pharmacotherapy. 2022-06-01
10.1016/j.biopha.2022.112994

Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model
Nadia Di Franco, Guillaume Drutel, Valérie Roullot-Lacarrière, Francisca Julio-Kalajzic, Valérie Lalanne, Agnès Grel, Thierry Leste-Lasserre, Isabelle Matias, Astrid Cannich, Delphine Gonzales, Vincent Simon, Daniela Cota, Giovanni Marsicano, Pier Vincenzo Piazza, Monique Vallée, Jean-Michel Revest
Molecular and Cellular Neuroscience. 2022-03-01
10.1016/j.mcn.2022.103705

Functional heterogeneity of POMC neurons relies on mTORC1 signaling
Nicolas Saucisse, Wilfrid Mazier, Vincent Simon, Elke Binder, Caterina Catania, Luigi Bellocchio, Roman A. Romanov, Stéphane Léon, Isabelle Matias, Philippe Zizzari, Carmelo Quarta, Astrid Cannich, Kana Meece, Delphine Gonzales, Samantha Clark, Julia M. Becker, Giles S.H. Yeo, Xavier Fioramonti, Florian T. Merkle, Sharon L. Wardlaw, Tibor Harkany, Federico Massa, Giovanni Marsicano, Daniela Cota
Cell Reports. 2021-10-01
10.1016/j.celrep.2021.109800

mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin.
Magalie Haissaguerre, Amandine Ferrière, Vincent Simon, Nicolas Saucisse, Nathalie Dupuy, Caroline André, Samantha Clark, Omar Guzman-Quevedo, Antoine Tabarin, Daniela Cota
Molecular Metabolism. 2018-06-01
10.1016/j.molmet.2018.04.002